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5.1 Translational relevance of NSC-based therapy The regenerative potential of NSCs has attracted considerable attention as a therapeutic strategy for neurodegenerative diseases and pathologies of CNS, also including trauma and ischemic injury (Zhou et al., 2019)

3,15 Distinct from apoptosis, autophagy, and pyroptosis, ferroptosis is a unique form of iron-dependent regulated cell death

These results suggested that RGSH intervention could restore the changes in ferroptosis-related proteins induced by the ferroptosis inducers, thereby inhibiting ferroptosis

When the valves fail, this causes a further increase in pressure and blood pooling in the legs which becomes a vicious cycle of increased pressure and further venous distention

Chemico-Biological Interactions, 212 , 3039