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Concurrently, vitamin B12 deficiency was identified as a significant public health concern, particularly among vulnerable populations such as the elderly and developing embryos, where insufficient B12 levels have been associated with an increased risk of neural tube defects

Am J Physiol

Search strategy Two reviewers (LM, DF) systematically searched MEDLINE, Embase, and the Cochrane Library from inception to August 2023 using a comprehensive search strategy combining study design-, intervention-, and diagnosis-related search terms (see Table 1 for a complete list of antioxidants included in the review)

But some people have up to 12 infusions

MW: Writing review & editing, Conceptualization, Validation, Visualization

Ferroptosis, but not necroptosis, is important in nephrotoxic folic acid-induced AKI