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The Crash and Downregulation The brain tries to protect itself from this overwhelming surge by turning down the volume. It reduces the number of receptors available to receive these chemical signals (a process called downregulation)

Opponents point out that the majority of people who have become ill due to vaping had used products with THC, or tetrahydrocannabinol, mostly those acquired illegally

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Available therapies include nasal saline drops, antidepressants, antiseizure medications, and sedatives

Instruct the patient to begin taking Vestura either on the first day of her menstrual period (Day 1 Start) or on the first Sunday after the onset of her menstrual period (Sunday Start)